Global Phosphatidylserine Market Size, Share and Future Trends Analysis Report By Nature (Organic, Conventional), By Source (Meat, Fish, Plants), By Forms (Powder, Liquid, Capsule), By Application (Dietary Supplements, Functional Food, Medical Food, Others), By Distribution Channel (Online, Offline) , Region and Companies - Industry Segment Outlook, Market Assessment, Competition Scenario, Trends and Forecast 2025-2034

Report Overview

The Global Phosphatidylserine Market size is expected to be worth around USD 241.6 Million by 2034, from USD 158.6 Million in 2024, growing at a CAGR of 4.3% during the forecast period from 2025 to 2034.

Phosphatidylserine (PS) concentrates are specialized lipid compounds predominantly used in dietary supplements and pharmaceuticals due to their critical role in cognitive function, memory enhancement, and neurological health. Derived mainly from soy lecithin or sunflower lecithin, these concentrates have gained traction in the nutraceutical and functional food industries as demand for brain health supplements rises globally. PS serves as an essential phospholipid in cell membranes, especially in brain cells, making its concentrates valuable for preventing cognitive decline and supporting mental wellness.

The industrial scenario for phosphatidylserine concentrates is shaped by increasing consumer awareness around cognitive health, an aging global population, and rising incidences of neurodegenerative diseases such as Alzheimer’s and dementia. According to the World Health Organization (WHO), by 2050, the number of people aged 60 years and older is expected to reach 2 billion globally, up from 900 million in 2015, thus driving the need for brain health-related supplements. This demographic shift is a key driver for the growing production and consumption of PS concentrates in both developed and emerging markets.

Driving factors for the phosphatidylserine concentrates market include growing consumer inclination towards brain health supplements, increased incidences of neurodegenerative diseases such as Alzheimer’s, and expanding applications in sports nutrition for stress reduction and cognitive enhancement. The World Health Organization reports that around 55 million people globally live with dementia, with 10 million new cases annually, emphasizing the urgent need for supportive nutritional interventions. This epidemiological data underpins the increasing adoption of PS concentrates.

Government initiatives such as the National Institute on Aging (NIA) in the United States have allocated funding to investigate dietary supplements supporting cognitive health, indirectly supporting phosphatidylserine research and commercialization. For instance, in 2023, the NIA increased its budget for cognitive health research by approximately 12% to US$500 million, reflecting the rising focus on aging-related cognitive disorders.

Future growth opportunities for the phosphatidylserine concentrates market are robust, supported by technological innovation and expanding applications beyond cognitive health. Emerging research suggests potential benefits in sports nutrition for enhancing focus and stress management, opening new avenues for product diversification. Additionally, government initiatives aimed at aging population care—such as the European Union’s Horizon Europe program, which earmarked over €95 billion from 2021 to 2027 for health-related research—can accelerate development and adoption of PS-based supplements.

Key Takeaways

• Phosphatidylserine Market size is expected to be worth around USD 241.6 Million by 2034, from USD 158.6 Million in 2024, growing at a CAGR of 4.3%.
• Conventional phosphatidylserine held a dominant market position, capturing more than a 94.6% share.
• Plant-based phosphatidylserine held a dominant market position, capturing more than a 74.8% share.
• Powder form of phosphatidylserine held a dominant market position, capturing more than a 65.9% share.
• Dietary supplements held a dominant market position in the phosphatidylserine industry, capturing more than a 45.2% share.
• Offline distribution held a dominant market position in the phosphatidylserine market, capturing more than a 76.4% share.
• North America emerged as the leading region in the global phosphatidylserine market, commanding a substantial share of 42.9%, translating to approximately USD 68.0 million.

By Nature

Conventional phosphatidylserine leads with over 94.6% market share in 2024, driven by established production methods and strong demand.

In 2024, conventional phosphatidylserine held a dominant market position, capturing more than a 94.6% share of the overall phosphatidylserine market. This strong hold can be attributed to the well-established extraction processes primarily using soy and other traditional plant-based sources, which have proven reliable and cost-effective for manufacturers. Conventional PS continues to be preferred by many companies due to its consistent quality, regulatory acceptance, and wide availability.

The conventional segment has maintained its lead thanks to steady production capabilities and trusted supply chains. Despite growing interest in alternative and novel sources, conventional phosphatidylserine remains the backbone of the market, supporting both dietary supplements and pharmaceutical applications. Its widespread adoption is reinforced by government approvals and long-standing consumer trust, keeping it at the forefront of the industry through this period.

By Source

Plant-based phosphatidylserine leads with over 74.8% share in 2024, reflecting strong consumer preference for natural sources.

In 2024, plant-based phosphatidylserine held a dominant market position, capturing more than a 74.8% share of the overall phosphatidylserine market. This preference is largely driven by increasing consumer demand for natural and sustainable ingredients, with soy and sunflower lecithin being the primary sources. The plant-derived segment has seen consistent growth due to advancements in extraction technologies that improve purity and yield.

Additionally, regulatory support for plant-based phosphatidylserine, especially from agencies like the U.S. FDA, has helped boost confidence among manufacturers and consumers alike. The shift towards plant sources aligns well with global trends favoring environmentally friendly and non-animal derived products. This has ensured that the plant-based segment remains the most significant contributor to the phosphatidylserine market during this period.

By Forms

Powder form dominates with over 65.9% share in 2024 due to its versatility and ease of use.

In 2024, the powder form of phosphatidylserine held a dominant market position, capturing more than a 65.9% share of the overall market. This preference stems from the powder’s flexibility, allowing manufacturers to easily incorporate it into a variety of products such as capsules, tablets, and functional foods. The powder segment has consistently outperformed other forms thanks to its longer shelf life, convenient dosage control, and cost-effective transportation.

Additionally, powder phosphatidylserine supports better formulation stability compared to liquid or other forms, making it the preferred choice for supplement companies worldwide. This has ensured the powder form maintains its leading role in the market throughout this period.

By Application

Dietary supplements lead with over 45.2% share in 2024, driven by growing consumer focus on brain health.

In 2024, dietary supplements held a dominant market position in the phosphatidylserine industry, capturing more than a 45.2% share. This strong presence is attributed to increasing consumer awareness around cognitive health, memory support, and stress reduction benefits that phosphatidylserine offers. From 2023 through 2025, the dietary supplement segment consistently grew as more people, especially aging populations, sought natural ways to support mental well-being.

The availability of phosphatidylserine in easy-to-consume supplement formats like capsules and powders has also fueled its widespread adoption. Regulatory approvals and health campaigns encouraging proactive brain health management further bolstered this segment’s expansion during this time. As a result, dietary supplements remain the largest application area for phosphatidylserine products.

By Distribution Channel

Offline distribution leads with over 76.4% share in 2024 due to widespread retail accessibility and consumer trust.

In 2024, offline distribution held a dominant market position in the phosphatidylserine market, capturing more than a 76.4% share. This dominance is largely due to the extensive network of pharmacies, health stores, and specialty supplement outlets that remain preferred channels for many consumers.

offline sales continued to outperform other channels, supported by consumers’ trust in physically inspecting products and seeking advice from in-store experts. Despite the rise of e-commerce, the convenience and personalized experience offered by offline retailers have helped maintain this channel’s lead. Additionally, government regulations and product approvals often favor traditional retail environments, further solidifying offline’s role in the market during this period.

Key Market Segments

By Nature

• Organic
• Conventional

By Source

• Meat
• Fish
• Plants

By Forms

• Powder
• Liquid
• Capsule

By Application

• Dietary Supplements
• Functional Food
• Medical Food
• Others

By Distribution Channel

• Online
• Offline

Drivers

Growing Awareness of Cognitive Health Driving Phosphatidylserine Demand

In 2024, increasing awareness about brain health and cognitive function has emerged as a major driving factor for the phosphatidylserine market. Phosphatidylserine is recognized for its potential benefits in enhancing memory, focus, and mental clarity, especially among aging populations and individuals experiencing cognitive decline. The global rise in neurodegenerative conditions like Alzheimer’s disease and dementia is encouraging consumers to seek natural supplements to support brain health, thus boosting demand for phosphatidylserine.

The World Health Organization (WHO) estimates that around 55 million people worldwide live with dementia, and this number is expected to rise to 78 million by 2030. This alarming statistic is pushing governments and healthcare bodies to promote preventive health measures, including dietary supplements that support cognitive function. For instance, the U.S. National Institutes of Health (NIH) highlights phosphatidylserine as a promising supplement for cognitive enhancement, particularly in older adults.

Additionally, leading food and nutrition organizations are emphasizing brain-healthy diets. The Global Council on Brain Health (GCBH), backed by AARP, encourages the consumption of nutrients like phosphatidylserine to maintain mental sharpness. This growing endorsement from trusted health bodies increases consumer confidence and market acceptance.

Government initiatives also play a key role. Many countries are launching awareness campaigns on aging health and cognitive wellness, indirectly supporting supplements like phosphatidylserine. For example, the National Institute on Aging (NIA) under the U.S. Department of Health and Human Services promotes research and education around brain health, which fosters greater interest in neuro-supportive ingredients.

Restraints

Limited Awareness and High Cost Restrict Phosphatidylserine Market Growth

Despite its benefits, one major restraining factor for the phosphatidylserine market in 2024 is limited consumer awareness combined with its relatively high cost compared to other dietary supplements. Many people, especially in developing regions, are still unfamiliar with phosphatidylserine and its role in supporting brain health. This lack of awareness restricts the product’s reach and acceptance, slowing overall market growth.

According to data from the Food and Agriculture Organization (FAO), dietary supplement usage remains concentrated in developed countries, where awareness and affordability are higher. In lower-income regions, less than 20% of adults regularly use supplements, primarily due to limited knowledge and financial constraints. Phosphatidylserine, being a specialty ingredient, is often priced higher than more common supplements like vitamins or minerals, making it less accessible for price-sensitive consumers.

The cost factor is also influenced by the complexity of sourcing and manufacturing phosphatidylserine. Natural sources such as soy lecithin or sunflower lecithin require specific processing techniques, which add to production expenses. This makes the final product more expensive, further limiting its adoption.

Additionally, government healthcare initiatives often prioritize communicable diseases and basic nutrition programs, especially in emerging markets. Brain health supplements like phosphatidylserine do not receive as much focus or funding, which reduces public outreach and educational campaigns that could boost awareness.

For example, the World Health Organization’s (WHO) global nutrition strategies emphasize essential vitamins and minerals to combat malnutrition but have not strongly incorporated brain-health supplements, which affects the promotion and availability of products like phosphatidylserine.

Opportunity

Expansion in Sports Nutrition and Mental Wellness Segments Boosts Phosphatidylserine Market Growth

In 2024, one of the most promising growth opportunities for the phosphatidylserine market lies in its expanding application within sports nutrition and mental wellness sectors. Athletes and fitness enthusiasts increasingly recognize the benefits of phosphatidylserine for reducing exercise-induced stress and improving focus and recovery, which is driving demand in sports supplements. This trend opens new avenues beyond traditional brain health supplements.

The American College of Sports Medicine (ACSM) reports that over 50 million adults in the U.S. actively engage in regular exercise and fitness programs. Many of these consumers seek supplements that support both physical endurance and mental clarity, making phosphatidylserine an attractive ingredient for this audience. Studies suggest that phosphatidylserine can lower cortisol levels—the stress hormone released during intense workouts—helping athletes recover faster and maintain peak performance.

Mental wellness is another area gaining momentum globally. The World Health Organization (WHO) estimates that depression and anxiety disorders affect more than 320 million people worldwide. Governments and health organizations are increasingly focusing on mental health awareness and holistic approaches to wellbeing, which include nutrition-based interventions. This supportive environment encourages the incorporation of supplements like phosphatidylserine to help improve mood and cognitive function.

Furthermore, government initiatives such as the U.S. National Institute of Mental Health’s (NIMH) efforts to promote research into natural supplements for mental health provide credibility and visibility to ingredients like phosphatidylserine. Such support fosters innovation and product development, driving market expansion.

Trends

Increasing Demand for Plant-Based Phosphatidylserine Supplements

One of the most notable trends in the phosphatidylserine market in 2024 is the growing consumer preference for plant-based sources of this cognitive health supplement. Traditionally, phosphatidylserine was derived from animal sources like bovine brains and soy lecithin. However, with rising concerns over animal welfare and dietary restrictions, there is a significant shift towards plant-derived phosphatidylserine, particularly from sunflower lecithin.

This growth is driven by increasing consumer demand for natural and plant-based supplements that support brain health. Plant-based phosphatidylserine is not only suitable for vegetarians and vegans but also appeals to a broader audience seeking ethical and sustainable products. In response to this trend, companies are focusing on improving extraction techniques and offering organic-certified phosphatidylserine products. Advancements in extraction methods, such as supercritical CO₂ extraction, have enhanced the purity and bioavailability of plant-derived phosphatidylserine, making it a more attractive option for consumers.

Furthermore, the rise of e-commerce platforms and online retail channels has made it easier for consumers to access a variety of plant-based phosphatidylserine supplements. This accessibility has contributed to the market’s expansion, particularly in regions like North America and Asia-Pacific, where health-conscious consumers are increasingly seeking plant-based alternatives.

Regional Analysis

In 2024, North America emerged as the leading region in the global phosphatidylserine market, commanding a substantial share of 42.9%, translating to approximately USD 68.0 million in market value. This dominance is primarily attributed to the region’s heightened awareness of cognitive health, robust healthcare infrastructure, and a growing inclination towards dietary supplements among consumers. The United States, in particular, stands out as a significant contributor to this market share, driven by its aging population and increasing prevalence of cognitive health concerns.

The surge in demand for phosphatidylserine supplements in North America is closely linked to the rising incidence of age-related cognitive decline, including conditions such as Alzheimer’s disease and general memory impairment. As consumers become more proactive about mental wellness, there’s a noticeable shift towards supplements that support brain health, with phosphatidylserine being a key ingredient due to its potential benefits in enhancing memory and focus.

Additionally, the region’s well-established retail and e-commerce platforms have facilitated easy access to a variety of phosphatidylserine products. Major health and wellness retailers, both online and offline, have expanded their offerings to include these supplements, catering to the growing consumer demand. This accessibility, combined with consumer education on cognitive health, has further propelled the market’s growth in North America.

Key Regions and Countries

• North America
  • US
  • Canada
• Europe
  • Germany
  • France
  • The UK
  • Spain
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • South Korea
  • India
  • Australia
  • Rest of APAC
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC
  • South Africa
  • Rest of MEA

Key Players Analysis

Chemi Nutra LLC specializes in the development and supply of high-quality phosphatidylserine ingredients, focusing on natural and sustainable sourcing. The company caters to dietary supplement manufacturers worldwide, emphasizing innovation in ingredient formulation and purity standards. Its commitment to research and quality control has strengthened its presence in the phosphatidylserine market. Chemi Nutra actively collaborates with academic institutions to enhance product efficacy, targeting brain health and cognitive support sectors.

Doosan Corporation, a global conglomerate, operates across multiple industries including chemicals and nutrition. In the phosphatidylserine market, it leverages advanced extraction technologies and large-scale manufacturing capabilities. The company focuses on producing plant-based phosphatidylserine to meet growing consumer demand for vegan-friendly supplements. Doosan’s strategic investments in R&D and sustainable production align with global trends emphasizing health and environmental responsibility, positioning it as a key player in cognitive health ingredients.

Double Wood LLC is a US-based nutraceutical company known for its commitment to purity, transparency, and quality in dietary supplements. It offers phosphatidylserine among its portfolio of brain health products, targeting cognitive function enhancement. The company emphasizes third-party testing and GMP-compliant manufacturing, gaining trust among health-conscious consumers. Double Wood focuses on research-backed formulations and direct-to-consumer distribution channels, supporting growing demand for effective mental wellness supplements.

Top Key Players in the Market

• Chemi Nutra LLC
• Doosan Corporation
• Double Wood Llc.
• ECA Healthcare Inc.
• IvoVital Gmbh
• Jarrow Formulas Inc
• Lipogen Products Ltd.
• Lipoid GmbH
• Lonza AG -Enzymotec Ltd
• Nagase Chemtex Corporation
• Nature’s Way Products Llc.
• Novastell
• Solgar Inc.
• Swanson Health Products Inc.
• Xian Natural Field Bio-Technique Co. Ltd.

Recent Developments

In 2024 Jarrow Formulas Inc., PS100 is available in two primary packaging options: 60 softgels and 120 capsules. The 60-softgel bottle is priced at approximately $31.94, while the 120-capsule bottle is available for around $58.99. These products are widely distributed through various online retailers, including Amazon, Walmart, and the official Jarrow Formulas website.

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