Market.us announces publication of its most recently generated research report titled, “Global Mixed-mode Chromatography Resin Market by Product Type (Ion Exchange- Hydrophobic, Hydroxyapatite, Other Types), By Application (Pharmaceutical and Biotechnology, Research Institutes, Contract Research Organizations (CRO), Other End-Use Industry) and by Region – Global Forecast to 2029”, which offers a holistic view of the global mixed-mode chromatography resin market through systematic segmentation that covers every aspect of the target market.

The global mixed-mode chromatography resin market is projected to be US$ 132.0 Mn in 2019 to reach US$ 273.9 Mn by 2029 at a CAGR of 7.6%.

Chromatography is the process that is used to separate the solution into its components. This is a technique that is adopted to separate both organic compounds as well as inorganic compounds. There are two distinct phases in chromatography: the mobile phase and the stationary phase. When the mobile phase passes through the stationary phase, they identify and collect the component that needs to be tested. The process can be divided into three steps: capture, purification, and polishing. The chromatography is classified broadly into four major categories: liquid chromatography, gas chromatography, thin-layer chromatography, and paper chromatography. Among these, the most extensively used is liquid chromatography. In liquid chromatography, resins are used which bind or repel particles and help to identify highly complex proteins in a solution. There are different types of chromatography, which can be classified based on resins used. They can be classified into affinity, ion- exchange, hydrophobic interactions, and exclusions.

Mixed-mode chromatography is one of the best-known techniques used in separation and employs both reverse-phase interactions as well as ion-exchange interactions. It can be classified into two major categories, namely: physical method and the chemical methods. Mixed-mode chromatography is used for protein adsorption by using various combinations of interactions between the particles. There are several combinations of mixed-mode materials available. The interaction and the bonding largely depend on the pH value of the solution as well as the ionic properties of the solution. In the mono-modal chromatographic technique, the separation takes place based on the specific interaction between the particles. The mixed-mode chromatography does not employ any particular interaction. The target molecules will interact based on the affinity, and it will deliver the optimal selectivity.

Global Mixed-mode Chromatography Resin Market Revenue (US$ Mn), 2019–2029

Monoclonal Antibodies (mAbs) have very high commercial potential in the pharmaceutical industry. The manufacturing process is affected by the downstream process used in the development of pharmaceuticals. Multi-modal chromatography provides an optimal solution for the production of mAbs, which is a factor proliferating growth of the target market. Mixed-mode chromatography offers the best solution for the specific selection of compounds. So through alterations in the ionic strengths, pH, the molecules can be separated easily. It provides flexibility to separate the components in the solution depending on the needs of the experiment. This is a factor expected to boost the revenue growth of the mixed-mode chromatography resin market.

Several new diseases are being born all over the world, which puts tremendous pressure on the pharmaceutical industry to identify the various proteins that are present in the host body. The mixed-mode resin-based chromatography provides the necessary flexibility to perform the experiments with selective retention capability, which in turn is expected to drive the target market growth. Developed countries such as the USA and European markets have been performing a large scale of R& D in their countries in the area of pharmaceuticals. These markets are increasing their use of Mixed-mode chromatography to perform separation and analysis. Hence they form a major driver for the growth of Mixed-mode Chromatography in these areas.

Mixed-mode chromatography techniques require equipment, which is very costly. Furthermore, the chromatography techniques require highly trained professionals who can operate the equipment. This increases the operational cost, which is a factor hampering growth of the target market.

Global Mixed-mode Chromatography Resin Market Attractiveness Analysis by Product Type, 2013–2019

Based on the region, the market is segmented into North America, Europe, APAC, and other regions. North America owns the majority share in the global Mixed-mode Chromatography Resin market, followed by Europe, owing to the robust industrialization in these regions.

The global mixed-mode chromatography resin market includes profiles of some of the major companies such as General Electric Company, Danaher Corporation, Merck KGaA, Tosoh Corporation, HOYA Corporation, Bio-Rad Laboratories, Inc., and others.

Key Market Segments:

Type

• Ion Exchange-Hydrophobic
• Hydroxyapatite

Application

• Monoclonal Antibodies
• Non-antibody Protein
• Polyclonal Antibodies

Key Market Players included in the report:

• General Electric Company
• Danaher Corporation
• Merck KGaA
• Tosoh Corporation
• HOYA Corporation
• Bio-Rad Laboratories Inc.

For the Mixed-mode Chromatography Resin Market research study, the following years have been considered to estimate the market size: