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Home ➤ Life Science ➤ Pharmaceuticals ➤ Epinephrine Market
Epinephrine Market
Epinephrine Market
Published date: Sep 2024 • Formats:
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  • Home ➤ Life Science ➤ Pharmaceuticals ➤ Epinephrine Market

Epinephrine Market By Product Type (Auto-injector, Prefilled Syringe, Ampoules, and Vials), By Application (Anaphylaxis, Superficial Bleeding, Cardiac Arrest, Respiratory Disorders, and Others), By Distribution Channel (Retail Pharmacies, Hospital Pharmacies, and Online Pharmacies), Region and Companies – Industry Segment Outlook, Market Assessment, Competition Scenario, Trends and Forecast 2024-2033

  • Published date: Sep 2024
  • Report ID: 129181
  • Number of Pages: 322
  • Format:
  • Overview
  • Table of Contents
  • Major Market Players
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    • Report Overview
    • Key Takeaways
    • Product Type Analysis
    • Application Analysis
    • Distribution Channel Analysis
    • Key Market Segments
    • Drivers
    • Restraints
    • Opportunities
    • Impact of Macroeconomic / Geopolitical Factors
    • Latest Trends
    • Regional Analysis
    • Key Players Analysis
    • Recent Developments
    • Report Scope

    Report Overview

    The Epinephrine Market size is expected to be worth around USD 6.3 billion by 2033 from USD 2.8 billion in 2023, growing at a CAGR of 8.4% during the forecast period 2024 to 2033.

    Epinephrine Market Size

    Increasing cases of allergies and severe allergic reactions, such as anaphylaxis, are driving demand for epinephrine in the market. Epinephrine, widely used for emergency treatment of life-threatening allergic reactions, plays a critical role in managing conditions such as anaphylaxis, asthma attacks, and cardiac arrest. According to Pubmed Central, nearly 5% of the U.S. population has experienced anaphylaxis, highlighting the growing need for effective treatment options.

    Additionally, data from the CDC in 2021 revealed that 6.2% of U.S. adults suffer from food allergies, further underscoring the importance of epinephrine auto-injectors. The prevalence of allergic rhinitis, affecting 20.9% of people aged 20-44 in Europe, and the fact that over 50 million Americans suffer from allergies annually, provide significant growth opportunities for epinephrine solutions. Recent trends focus on improving auto-injector devices, enhancing affordability, and expanding public access to epinephrine, ensuring timely and effective treatment for allergic emergencies.

    Key Takeaways

    • In 2023, the market for Epinephrine generated a revenue of USD 2.8 billion, with a CAGR of 8.4%, and is expected to reach USD 6.3 billion by the year 2033.
    • The product type segment is divided into auto-injector, prefilled syringe, ampoules, and vials, with auto-injector taking the lead in 2023 with a market share of 52.3%.
    • Considering application, the market is divided into anaphylaxis, superficial bleeding, cardiac arrest, respiratory disorders, and others. Among these, anaphylaxis held a significant share of 46.8%.
    • Furthermore, concerning the distribution channel segment, the market is segregated into retail pharmacies, hospital pharmacies, and online pharmacies. The hospital pharmacies sector stands out as the dominant player, holding the largest revenue share of 48.7% in the Epinephrine market.
    • North America led the market by securing a market share of 40.2% in 2023.

    Product Type Analysis

    The auto-injector segment led in 2023, claiming a market share of 52.3% owing to its ease of use and the rising prevalence of severe allergic reactions. Auto-injectors, designed for rapid and self-administration, are becoming the preferred choice for patients managing conditions like anaphylaxis.

    Increased awareness of the life-saving potential of auto-injectors and their availability in user-friendly designs have driven demand. The rising incidence of food allergies and insect stings, particularly in children, has contributed to this growth. Technological advancements in auto-injector designs, including compact and portable models, are likely to further boost adoption rates, enhancing segment growth over the forecast period.

    Application Analysis

    The anaphylaxis held a significant share of 46.8% due to the rising global prevalence of severe allergic reactions. Increasing incidences of food allergies, drug reactions, and insect stings that lead to life-threatening anaphylactic shocks are boosting demand for epinephrine-based treatments. Growing awareness among healthcare professionals and patients about the importance of early intervention in anaphylaxis management has also contributed to the segment’s expansion.

    Additionally, government initiatives to improve access to epinephrine auto-injectors, particularly in schools and public places, are expected to support the growth of this segment. Advances in treatment protocols and guidelines for anaphylaxis management further drive this market segment.

    Distribution Channel Analysis

    The hospital pharmacies segment had a tremendous growth rate, with a revenue share of 48.7% owing to the critical role hospitals play in emergency care. As hospitals often serve as the first point of treatment for acute allergic reactions and anaphylaxis, the demand for epinephrine products in these settings remains high.

    Hospital pharmacies also provide access to a wide range of epinephrine delivery systems, including auto-injectors and prefilled syringes, for immediate administration during emergencies. Rising hospital admissions related to severe allergic reactions, along with the expansion of healthcare infrastructure in emerging markets, is anticipated to drive this segment’s growth. The emphasis on maintaining a sufficient stock of emergency medications in hospitals further supports the expansion of hospital pharmacies.

    Epinephrine Market Share

    Key Market Segments

    By Product Type

    • Auto-injector
    • Prefilled Syringe
    • Ampoules
    • Vials

    By Application

    • Anaphylaxis
    • Superficial Bleeding
    • Cardiac Arrest
    • Respiratory Disorders
    • Others

    By Distribution Channel

    • Retail Pharmacies
    • Hospital Pharmacies
    • Online Pharmacies

    Drivers

    Growing Prevalence of Asthma

    The increasing prevalence of asthma continues to drive the demand for epinephrine, particularly in emergency treatments for severe asthma attacks. Asthma affects millions of individuals globally, and its prevalence remains notably high among both children and adults. For instance, data published by the National Center for Biotechnology Information (NCBI) in 2022 indicate that asthma affects 4.0% to 6.0% of adults and 10.0% of children in Germany.

    With asthma becoming a chronic condition for many patients, the need for fast-acting treatments such as epinephrine auto-injectors becomes crucial. This growing incidence is anticipated to fuel the epinephrine market, as more healthcare providers prescribe it for managing acute exacerbations and preventing life-threatening complications.

    Restraints

    High Cost of Auto-injectors

    Rising costs of auto-injectors significantly hamper the epinephrine market, limiting access for many patients in need of emergency treatment. The high price of these devices creates financial barriers for individuals, especially those without comprehensive insurance coverage. Even though epinephrine is a critical medication for anaphylaxis and severe asthma attacks, the cost of auto-injectors remains disproportionately high.

    This pricing issue is anticipated to impede market growth, particularly in developing regions where healthcare resources and affordability are already constrained. The high costs also limit public health programs from distributing auto-injectors on a large scale, thus restraining widespread adoption and access to this life-saving solution.

    Opportunities

    Increasing Occurrence  of Cardiac Arrests

    The increasing occurrence of cardiac arrests offers a substantial opportunity for the epinephrine market, as the medication plays a key role in emergency resuscitation efforts. Cardiac arrest remains a leading cause of death globally, with more than 356,000 out-of-hospital cardiac arrests (OHCA) annually in the U.S., as reported by the American Heart Association.

    Alarmingly, nearly 90% of these cases are fatal, underscoring the need for rapid intervention. Epinephrine is expected to be a vital tool in improving survival rates during such emergencies, as it helps restore normal heart function. As the number of cardiac arrests continues to rise, healthcare systems are projected to increase demand for epinephrine in emergency medical settings, presenting a notable growth opportunity for the market.

    Impact of Macroeconomic / Geopolitical Factors

    Macroeconomic and geopolitical factors have a profound impact on the epinephrine market, influencing both supply and demand dynamics. Economic downturns can reduce healthcare budgets, leading to constrained access to life-saving drugs in certain regions. Geopolitical tensions and trade barriers may disrupt global supply chains, causing shortages and increased costs for raw materials, which can affect drug availability.

    However, government regulations aimed at ensuring access to essential medicines provide growth opportunities in established markets. Emerging economies, with improving healthcare infrastructures, also present new avenues for expansion. Despite these challenges, continuous innovation and strategic partnerships are contributing to the increased availability of epinephrine products globally.

    Latest Trends

    Rise in Collaborations among Key Players

    Rising collaborations among key players are driving significant growth in the epinephrine market. Pharmaceutical companies are joining forces to streamline the development, approval, and commercialization of new formulations. In July 2022, ARS Pharmaceuticals and Silverback Therapeutics formed a partnership for the regulatory approval and commercialization of Neffy, an epinephrine nasal spray.

    This collaboration is anticipated to enhance product accessibility and expand treatment options for patients. Increased partnerships in the industry are projected to foster innovation, expedite regulatory processes, and improve market penetration. As a result, the market is likely to see robust growth, providing better solutions for managing severe allergic reactions.

    Regional Analysis

    North America is leading the Epinephrine Market

    North America dominated the market with the highest revenue share of 40.2% owing to an increase in allergic reactions, particularly anaphylaxis, among the population. The rising incidence of food allergies and environmental allergens contributed significantly to the demand for epinephrine auto-injectors, which provide immediate relief in life-threatening situations.

    Pharmaceutical companies have capitalized on this growing demand by expanding product availability and enhancing distribution networks. For instance, in May 2020, kaleo, Inc. announced the availability of the ALLERJECT auto-injector in Canada, providing Canadian patients with additional treatment options for anaphylaxis. Increased awareness of severe allergic reactions and advancements in epinephrine delivery systems have further bolstered market growth across North America.

    The Asia Pacific region is expected to experience the highest CAGR during the forecast period

    Asia Pacific is expected to grow with the fastest CAGR owing to increasing awareness of allergies and rising healthcare investments. Major pharmaceutical companies are anticipated to expand their presence through strategic partnerships and product launches. In July 2021, ALK-Abelló A/S partnered with Grandpharma to launch its adrenaline auto-injector, “Jext,” in China, marking the introduction of the first auto-injector in the country.

    This move highlights the growing demand for emergency allergy treatments in the region. As healthcare infrastructure improves and awareness of anaphylaxis rises, the market is likely to experience accelerated growth, particularly in emerging economies like China and India.

    Epinephrine Market Regions

    Key Regions and Countries

    • North America
      • US
      • Canada
    • Europe
      • Germany
      • France
      • The UK
      • Spain
      • Italy
      • Russia
      • Netherland
      • Rest of Europe
    • Asia Pacific
      • China
      • Japan
      • South Korea
      • India
      • Australia
      • New Zealand
      • Singapore
      • Thailand
      • Vietnam
      • Rest of APAC
    • Latin America
      • Brazil
      • Mexico
      • Rest of Latin America
    • Middle East & Africa
      • South Africa
      • Saudi Arabia
      • UAE
      • Rest of MEA

    Key Players Analysis

    The major players in the Epinephrine market are actively engaged in the development and introduction of innovative products, as well as implementing strategic initiatives aimed at enhancing their competitive positioning. Key players in the epinephrine market focus on developing user-friendly auto-injectors and alternative delivery methods to enhance patient convenience and safety.

    They engage in partnerships with healthcare providers and pharmacies to expand distribution channels and improve product accessibility. Companies also invest in research to create cost-effective formulations, addressing affordability concerns in various markets. Strategic mergers and acquisitions help them strengthen their product portfolios and enter new geographic regions. Additionally, they implement educational campaigns to raise awareness about severe allergic reactions and the importance of timely treatment, driving product demand.

    Top Key Players in the Epinephrine Market

    • Pfizer
    • Nasus Pharma Ltd
    • Lincoln Medical Ltd.
    • Harvest Pharmaceuticals
    • Grand Pharma
    • Daiichi Sankyo, Inc.
    • ARS Pharmaceuticals
    • Abbott Laboratories

    Recent Developments

    • In December 2023: Nasus Pharma Ltd, a clinical-stage biopharmaceutical company, announced the successful completion of its additional Phase II clinical trial, which confirmed the efficacy and safety of its FMXIN002 Intranasal Epinephrine product. This advancement is significant for the epinephrine market as it demonstrates the potential for new, non-invasive delivery methods, expanding treatment options for allergic emergencies.
    • In March 2023: Daiichi Sankyo, Inc., through its subsidiary American Regent, Inc., launched a sulfite-free Epinephrine Injection, USP, designed for the emergency treatment of type I allergic reactions. This product launch contributes to the growth of the epinephrine market by providing a safer alternative for patients with sensitivities to sulfites, enhancing treatment accessibility.
    • In October 2022: ARS Pharmaceuticals announced that the FDA accepted the new drug application for its epinephrine nasal spray, Neffy. The acceptance of this innovative nasal spray format underscores the growing trend toward more user-friendly epinephrine delivery systems, driving further expansion of the epinephrine market.

    Report Scope

    Report Features Description
    Market Value (2023) USD 2.8 billion
    Forecast Revenue (2033) USD 6.3 billion
    CAGR (2024-2033) 8.4%
    Base Year for Estimation 2023
    Historic Period 2019-2022
    Forecast Period 2024-2033
    Report Coverage Revenue Forecast, Market Dynamics, COVID-19 Impact, Competitive Landscape, Recent Developments
    Segments Covered By Product Type (Auto-injector, Prefilled Syringe, Ampoules, and Vials), By Application (Anaphylaxis, Superficial Bleeding, Cardiac Arrest, Respiratory Disorders, and Others), By Distribution Channel (Retail Pharmacies, Hospital Pharmacies, and Online Pharmacies)
    Regional Analysis North America – US, Canada; Europe – Germany, France, The UK, Spain, Italy, Russia, Netherlands, Rest of Europe; Asia Pacific – China, Japan, South Korea, India, Australia, New Zealand, Singapore, Thailand, Vietnam, Rest of APAC; Latin America – Brazil, Mexico, Rest of Latin America; Middle East & Africa – South Africa, Saudi Arabia, UAE, Rest of MEA
    Competitive Landscape Pfizer, Nasus Pharma Ltd, Lincoln Medical, Ltd., Harvest Pharmaceuticals, Grand Pharma, Daiichi Sankyo, Inc., ARS Pharmaceuticals, and Abbott Laboratories.
    Customization Scope Customization for segments, region/country-level will be provided. Moreover, additional customization can be done based on the requirements.
    Purchase Options We have three licenses to opt for: Single User License, Multi-User License (Up to 5 Users), Corporate Use License (Unlimited User and Printable PDF)
    Epinephrine Market
    Epinephrine Market
    Published date: Sep 2024
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    • Pfizer Inc Company Profile
    • Nasus Pharma Ltd
    • Lincoln Medical Ltd.
    • Harvest Pharmaceuticals
    • Grand Pharma
    • Daiichi Sankyo, Inc.
    • ARS Pharmaceuticals
    • Abbott Laboratories
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