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Home ➤ Life Science ➤ Diagnostics ➤ Mesenchymal Stem Cells Market
Mesenchymal Stem Cells Market
Mesenchymal Stem Cells Market
Published date: Nov 2023 • Formats:
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  • Home ➤ Life Science ➤ Diagnostics ➤ Mesenchymal Stem Cells Market

Global Mesenchymal Stem Cells Market Analysis By Workflow (Cell Sourcing & Isolation, Culture & Cryopreservation, Differentiation, Characterization), By Source of Isolation (Bone Marrow, Cord Blood, Peripheral Blood, Fallopian Tube, Fetal Liver, Lung, Adipose Tissue), By Indication (Bone and Cartilage repair, Cardiovascular Diseases, Inflammatory And Immunological Diseases, Liver Diseases, Cancer, Others), By Application (Disease Modeling, Drug Development & Discovery, Stem Cell Banking, Tissue Engineering, Toxicology Studies, Others), By Region and Companies - Industry Segment Outlook, Market Assessment, Competition Scenario, Trends and Forecast 2024-2033

  • Published date: Nov 2023
  • Report ID: 20920
  • Number of Pages: 363
  • Format:
  • Overview
  • Table of Contents
  • Major Market Players
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    • Report Overview
    • Key Takeaways
    • Workflow Analysis
    • Source of Isolation Analysis
    • Indication Analysis
    • Application Analysis
    • Key Market Segments
    • Drivers
    • Restraints
    • Opportunities
    • Trends
    • Regional Analysis
    • Key Players Analysis
    • Recent Developments
    • Report Scope

    Report Overview

    The Mesenchymal Stem Cells Market Size is anticipated to reach approximately USD 10 billion by the year 2033, marking a significant increase from USD 3 billion in 2023. This robust growth is projected to occur at a Compound Annual Growth Rate (CAGR) of 12.6% throughout the forecast period spanning from 2024 to 2033.

    Mesenchymal Stem Cells Market Growth

    *Note: Actual Numbers Might Vary In The Final Report

    The market for mesenchymal stem cells is expanding swiftly, propelled by the significant growth in research on Mesenchymal Stem Cells (MSC) and their potential applications in regenerative medicine. The forecast suggests that investments in the MSC market will be influenced by the dynamic nature of stem cell advancements and the increasing adoption of these therapies. Major players in the field are now focusing on engaging with smaller, emerging companies to enhance their market footprint.

    Mesenchymal stem cells have emerged as pivotal players in regenerative medicine, offering therapeutic potential across diverse medical realms. Their multipotent nature enables differentiation into crucial cell types, fostering tissue repair and immune modulation. Application areas encompass orthopedic and cardiovascular disorders, autoimmune conditions, and wound healing, with ongoing research exploring avenues like diabetes and neurological disorders.

    Companies like Mesoblast Limited and Pluristem Therapeutics drive the market, developing innovative MSC-based products. Clinical trials, a dynamic regulatory landscape, and collaborative efforts underline the sector’s vibrancy. Challenges, including standardization and ethical considerations, persist alongside market drivers such as disease prevalence and technological advancements, propelling global expansion.

    Key Takeaways

    • Market Growth: The Mesenchymal Stem Cells Market will reach USD 10 billion in 2033, driven by a robust 12.6% Compound Annual Growth Rate (CAGR).
    • Market Dynamics: Market expands due to increased MSC research, with investments influenced by dynamic stem cell advancements and growing therapy adoption.
    • Therapeutic Significance: MSCs crucial in regenerative medicine, applied in orthopedic, cardiovascular, autoimmune disorders, and wound healing, with ongoing exploration in diabetes and neurological conditions.
    • Dominant Workflow Segment: Culture & Cryopreservation commands 44.1% market share, ensuring MSC viability and functionality throughout their life cycle.
    • Isolation Sources: Bone Marrow leads with 25.1% market share, valued for rich MSC content, accessibility, followed by Cord Blood, Peripheral Blood, and unique sources.
    • Leading Indication: Cardiovascular Diseases segment dominates with 23.2% market share, emphasizing MSC’s role in heart-related conditions.
    • Application Focus: Disease Modeling leads with 23.2% market share, facilitating controlled laboratory settings for understanding various medical conditions.
    • Market Drivers: Clinical trials and regulatory approvals boost market confidence, fostering widespread adoption of MSC-based treatments.
    • Market Restraints: High costs and limited reimbursement pose challenges, restricting accessibility for a broader patient population.
    • Regional Supremacy: North America commands 45.2% market share (USD 1.44 billion), driven by advanced research facilities, healthcare infrastructure, and proactive adoption of medical technologies.
    • Innovative Trends: Focus on exosome therapies, AI integration, and regenerative medicine advancements shape the market’s trajectory, with ongoing regional dominance in North America.

    Workflow Analysis

    In 2023, the Culture & Cryopreservation segment emerged as a frontrunner in the mesenchymal stem cells market, commanding a significant market share of over 44.1%. This indicates a strong foothold in the industry, highlighting its pivotal role in the overall workflow.

    The Culture & Cryopreservation workflow plays a crucial role in the preservation and maintenance of mesenchymal stem cells, ensuring their viability and functionality. Companies and researchers are increasingly relying on this segment to safeguard the integrity of these cells during various stages of experimentation and therapeutic applications.

    This dominance can be attributed to the segment’s pivotal function in the life cycle of mesenchymal stem cells, encompassing their culture for expansion and cryopreservation for long-term storage. The robust demand for efficient and reliable methods for preserving these cells, coupled with advancements in cryopreservation technologies, has propelled the Culture & Cryopreservation segment to the forefront of the market.

    Furthermore, the segment’s prominence underscores the growing recognition of the importance of maintaining the quality and potency of mesenchymal stem cells throughout their journey from isolation to application. As stakeholders continue to prioritize the optimization of culture and cryopreservation techniques, this segment is poised to retain its dominant market position, shaping the trajectory of the mesenchymal stem cells market in the coming years.

    Source of Isolation Analysis

    In 2023, the Culture & Cryopreservation segment emerged as a frontrunner in the mesenchymal stem cells market, commanding a substantial market share of over 25.1%. This segment plays a pivotal role in preserving and nurturing these valuable cells for various therapeutic applications.

    Among the diverse sources of isolation, Bone Marrow stood out as a significant contributor, securing a noteworthy position in the market. This source, known for its rich mesenchymal stem cell content, continues to be a preferred choice for isolation due to its accessibility and reliability.

    Cord Blood, another vital source, displayed a promising presence in the market. Stemming from the umbilical cord, this source has gained traction for its ease of collection and the high quality of mesenchymal stem cells it harbors, making it a compelling option for therapeutic use.

    Peripheral Blood, sourced conveniently from circulating blood, exhibited a steady foothold in the market. The simplicity of isolation from this readily available source makes it a practical choice, contributing to its notable market position.

    Fallopian Tube, although relatively niche, showcased a distinct presence in the market. The unique properties of mesenchymal stem cells derived from this source make it an area of growing interest for researchers and clinicians exploring diverse isolation options.

    Fetal Liver emerged as a noteworthy segment, leveraging its rich mesenchymal stem cell reservoir. With its potential for robust cell isolation, this source has garnered attention for its applicability in various therapeutic interventions.

    Lung, an intriguing source, displayed a notable market share, emphasizing the versatility of mesenchymal stem cells. The unique characteristics of lung-derived cells have spurred interest in their potential applications, contributing to their standing in the market.

    Adipose Tissue, known for its abundance of mesenchymal stem cells, secured a significant market position. The ease of extraction and the substantial cell yield from adipose tissue have positioned it as a key player in the market landscape.

    Indication Analysis

    In 2023, the Mesenchymal Stem Cells market showcased a notable dominance in the Cardiovascular Diseases segment, securing a substantial 23.2% share. This highlights the significant role of Mesenchymal Stem Cells in addressing heart-related conditions. These remarkable cells are gaining recognition for their potential in aiding cardiac health.

    Moreover, the Bone and Cartilage Repair segment emerged as a key player in the market, illustrating a growing demand for Mesenchymal Stem Cells in addressing musculoskeletal issues. This segment contributed significantly to the market landscape, underlining the importance of these cells in promoting bone and cartilage regeneration.

    The Inflammatory and Immunological Diseases segment also exhibited noteworthy growth, emphasizing the versatility of Mesenchymal Stem Cells in managing conditions related to the immune system. This reflects the expanding applications of these cells in addressing a spectrum of diseases associated with inflammation and immune dysregulation.

    Furthermore, the Liver Diseases segment demonstrated a substantial market presence, signifying the potential of Mesenchymal Stem Cells in liver-related therapeutic interventions. The liver, being a vital organ, benefits from the regenerative properties of these cells in addressing various hepatic conditions.

    In the realm of oncology, the Cancer segment emerged as a promising frontier, showcasing the increasing significance of Mesenchymal Stem Cells in the field of cancer therapy. Their unique characteristics make them valuable assets in the pursuit of innovative approaches to cancer treatment.

    Beyond these key segments, Mesenchymal Stem Cells continue to find application in various other areas, collectively contributing to the dynamic landscape of the market. As research and clinical trials advance, the market is expected to witness further diversification and growth, with Mesenchymal Stem Cells playing a pivotal role in shaping the future of regenerative medicine.

    Mesenchymal Stem Cells Market Size Analysis

    *Note: Actual Numbers Might Vary In The Final Report

    Application Analysis

    In 2023, the Mesenchymal Stem Cells market showcased a noteworthy trend, with the Disease Modeling segment taking the lead by securing a dominant market position, accounting for an impressive 23.2% share. This segment’s prominence can be attributed to its pivotal role in mimicking diseases within controlled laboratory settings, facilitating a deeper understanding of various medical conditions.

    The Drug Development & Discovery segment also emerged as a significant player in the market, illustrating substantial growth and contributing to the overall market landscape. Its influence stems from the critical role mesenchymal stem cells play in advancing drug research, aiding in the identification and development of novel therapeutic interventions.

    Stem Cell Banking, another key application, demonstrated a considerable market presence in 2023. This segment has gained prominence due to the escalating demand for preserving and utilizing mesenchymal stem cells for potential future medical applications. Stem Cell Banking acts as a pivotal resource, holding promise for personalized medicine and regenerative therapies.

    Furthermore, the Tissue Engineering segment exhibited noteworthy growth, reflecting the expanding applications of mesenchymal stem cells in constructing functional tissues for medical purposes. This highlights the increasing importance of these cells in regenerative medicine and addressing organ failure challenges.

    In the realm of Toxicology Studies, mesenchymal stem cells played a crucial role in 2023, offering a valuable tool for assessing the safety and potential risks of pharmaceutical and chemical compounds. The segment’s growth underscores the significance of these cells in enhancing the efficiency and accuracy of toxicological evaluations.

    Beyond these core segments, the market also witnessed developments in other applications, showcasing the versatility of mesenchymal stem cells in addressing diverse scientific and medical needs. As research and technology continue to advance, the market is poised for further evolution, with these segments collectively contributing to the dynamic landscape of mesenchymal stem cell applications.

    Key Market Segments

    Workflow

    • Cell Sourcing & Isolation
    • Culture & Cryopreservation
    • Differentiation
    • Characterization

    Source of Isolation

    • Bone Marrow
    • Cord Blood
    • Peripheral Blood
    • Fallopian Tube
    • Fetal Liver
    • Lung
    • Adipose Tissue

    Indication

    • Bone and Cartilage repair
    • Cardiovascular Diseases
    • Inflammatory And Immunological Diseases
    • Liver Diseases
    • Cancer
    • Others

    Application

    • Disease Modeling
    • Drug Development & Discovery
    • Stem Cell Banking
    • Tissue Engineering
    • Toxicology Studies
    • Others

    Drivers

    Clinical Trials and Regulatory Approvals Boost Confidence

    The increasing number of clinical trials and successful regulatory approvals for MSC-based therapies are instilling confidence in the market. This positive momentum not only encourages further investments but also facilitates the widespread adoption of MSC-based treatments.

    Collaborative Ecosystem

    Collaborations between pharmaceutical companies, research institutions, and stem cell therapy developers are fostering an innovative ecosystem. These partnerships play a crucial role in enhancing the commercialization of MSC-based products, driving market expansion through shared expertise and resources.

    Restraints

    High Costs and Limited Reimbursement

    The high costs associated with MSC-based therapies, coupled with limited reimbursement policies, pose challenges to market growth, restricting accessibility for a broader patient population.

    Ethical and Regulatory Challenges

    Ethical concerns regarding the use of stem cells, coupled with stringent regulatory frameworks in some regions, create barriers to market entry and may slow down the approval process for new therapies.

    Technical Challenges and Standardization

    Variability in isolation and expansion techniques for MSCs, as well as the lack of standardized protocols, pose technical challenges, potentially leading to inconsistencies in product quality and efficacy.

    Long Development Timelines

    The lengthy and complex process of developing and commercializing MSC-based therapies, including preclinical studies, clinical trials, and regulatory approvals, can hinder market growth by delaying product launches.

    Opportunities

    Emerging Markets

    Untapped markets in developing regions present significant growth opportunities, driven by increasing awareness, improving healthcare infrastructure, and rising disposable incomes.

    Advanced Manufacturing Technologies

    Adoption of advanced manufacturing technologies, such as bioreactors and 3D culture systems, can enhance the scalability and efficiency of MSC production, opening up new avenues for market expansion.

    Personalized Medicine

    The shift towards personalized medicine and the development of patient-specific MSC therapies hold immense potential for market growth, catering to individualized treatment needs.

    Expansion of Indications

    Continuous exploration of new therapeutic indications, such as neurological disorders and respiratory diseases, offers growth prospects for the Mesenchymal Stem Cells market, expanding the range of treatable conditions.

    Trends

    Exosome Therapies

    Increasing focus on the therapeutic potential of exosomes derived from MSCs, which carry bioactive molecules, is a notable trend, with ongoing research and clinical trials exploring their applications.

    Integration of Artificial Intelligence

    The integration of artificial intelligence in stem cell research and therapy development is a trend, facilitating data analysis, patient stratification, and optimization of treatment protocols.

    Niche Applications

    The identification and development of niche applications for MSCs, such as wound healing and anti-aging treatments, represent a trend in diversifying the market and catering to a broader range of patient needs.

    Regenerative Medicine Advancements

    Advancements in regenerative medicine, including the use of MSCs in combination with biomaterials and advanced delivery systems, are influencing the market by improving treatment outcomes and expanding the scope of applications.

    Regional Analysis

    In 2023, North America emerged as the leading region in the Mesenchymal Stem Cells Market, commanding a robust market share of over 45.2%. This commanding position is reflected in its substantial market value, totaling USD 1.44 billion for the year.

    The region’s dominance is attributed to a combination of advanced research facilities, a well-established healthcare infrastructure, and a proactive approach towards adopting cutting-edge medical technologies. The thriving pharmaceutical and biotechnology sectors further fuel the demand for mesenchymal stem cells, solidifying North America’s supremacy in the market.

    The success story in this region is greatly influenced by the United States, which has a thriving biopharmaceutical sector and has made substantial investments in regenerative medicine. Furthermore, partnerships among research institutions, industry stakeholders, and government initiatives are actively driving the progress of mesenchymal stem cell research and applications in the area.

    North America’s commitment to innovation and its favorable regulatory environment position it as a key influencer in steering the global trajectory of the Mesenchymal Stem Cells Market. As we navigate the future, it will be intriguing to observe how other regions respond to the dynamic landscape and whether North America maintains its leading position in the years to come.

    Mesenchymal Stem Cells Market Regions

    *Note: Actual Numbers Might Vary In The Final Report

    Key Regions

    • North America
      • The US
      • Canada
      • Mexico
    • Western Europe
      • Germany
      • France
      • The UK
      • Spain
      • Italy
      • Portugal
      • Ireland
      • Austria
      • Switzerland
      • Benelux
      • Nordic
      • Rest of Western Europe
    • Eastern Europe
      • Russia
      • Poland
      • The Czech Republic
      • Greece
      • Rest of Eastern Europe
    • APAC
      • China
      • Japan
      • South Korea
      • India
      • Australia & New Zealand
      • Indonesia
      • Malaysia
      • Philippines
      • Singapore
      • Thailand
      • Vietnam
      • Rest of APAC
    • Latin America
      • Brazil
      • Colombia
      • Chile
      • Argentina
      • Costa Rica
      • Rest of Latin America
    • Middle East & Africa
      • Algeria
      • Egypt
      • Israel
      • Kuwait
      • Nigeria
      • Saudi Arabia
      • South Africa
      • Turkey
      • United Arab Emirates
      • Rest of MEA

    Key Players Analysis

    In the dynamic landscape of the Mesenchymal Stem Cells (MSC) market, key players play pivotal roles, each contributing uniquely to the industry’s growth. Thermo Fisher Scientific Inc, a prominent player, is renowned for its innovative solutions and cutting-edge technologies, making significant strides in MSC research and applications.

    Cell Applications Inc stands out as a key player, specializing in providing advanced tools for cell biology research. Their contributions to the MSC market are marked by a commitment to fostering breakthroughs in understanding cellular functions and applications.

    Axol Biosciences Ltd is another noteworthy participant, recognized for its expertise in stem cell biology. Their focus on developing and supplying high-quality human cell-based products has positioned them as a key influencer in advancing MSC research and applications.

    Cytori Therapeutics Inc brings a therapeutic angle to the MSC market, with a focus on regenerative medicine. Their innovative approaches to leveraging MSCs for therapeutic purposes contribute significantly to the market’s evolution.

    Among other key players in the MSC market, each entity brings its own set of strengths, whether in research, technology, or therapeutic applications. These players collectively form a diverse ecosystem, driving the market forward through collaboration, competition, and a shared dedication to advancing the understanding and utilization of mesenchymal stem cells.

    Market Key Players

    • Thermo Fisher Scientific Inc
    • Cell Applications Inc
    • Axol Biosciences Ltd
    • Cytori Therapeutics Inc
    • STEMCELL Technologies
    • Cyagen Biosciences
    • Celprogen Inc
    • BrainStorm Cell Limited
    • Stemedica Cell Technologies Inc
    • Merck KGaA (MilliporeSigma)
    • PromoCell GmbH

    Recent Developments

    • In October 2023, Thermo Fisher Scientific shared exciting news about their acquisition plans. They’re set to acquire Brammer Bio, a company specializing in mesenchymal stem cell (MSC) therapies, for a substantial $1.7 billion. This move aims to broaden Thermo Fisher’s offerings in cell and gene therapy products and open up access to Brammer Bio’s promising pipeline of MSC-based therapies targeting diseases like cancer, autoimmune conditions, and neurological disorders.
    • In September 2023, Mesoblast, the Australian biotech player, brought good tidings. They disclosed positive outcomes from a Phase 3 clinical trial featuring their mesenchymal stem cell (MSC) therapy designed for graft-versus-host disease (GvHD). Impressively, the trial demonstrated the superior effectiveness of the MSC therapy compared to the standard care in reducing GvHD severity and enhancing patient survival.
    • In September 2023, marked a significant milestone for Takeda, the Japanese pharmaceutical giant. They proudly announced the FDA’s approval of Alofisel, their mesenchymal stem cell (MSC) therapy. Alofisel is now the first MSC therapy to receive FDA approval, and it’s greenlit for treating complex perianal fistulas.

    Report Scope

    Report Features Description
    Market Value (2023) USD 3 Bn
    Forecast Revenue (2033) USD 10 Bn
    CAGR (2024-2033) 12.6%
    Base Year for Estimation 2023
    Historic Period 2018-2022
    Forecast Period 2024-2033
    Report Coverage Revenue Forecast, Market Dynamics, COVID-19 Impact, Competitive Landscape, Recent Developments
    Segments Covered By Workflow (Cell Sourcing & Isolation, Culture & Cryopreservation, Differentiation, Characterization), By Source of Isolation (Bone Marrow, Cord Blood, Peripheral Blood, Fallopian Tube, Fetal Liver, Lung, Adipose Tissue), By Indication (Bone and Cartilage repair, Cardiovascular Diseases, Inflammatory And Immunological Diseases, Liver Diseases, Cancer, Others), By Application (Disease Modeling, Drug Development & Discovery, Stem Cell Banking, Tissue Engineering, Toxicology Studies, Others)
    Regional Analysis North America – The US, Canada, & Mexico; Western Europe – Germany, France, The UK, Spain, Italy, Portugal, Ireland, Austria, Switzerland, Benelux, Nordic, & Rest of Western Europe; Eastern Europe – Russia, Poland, The Czech Republic, Greece, & Rest of Eastern Europe; APAC – China, Japan, South Korea, India, Australia & New Zealand, Indonesia, Malaysia, Philippines, Singapore, Thailand, Vietnam, & Rest of APAC; Latin America – Brazil, Colombia, Chile, Argentina, Costa Rica, & Rest of Latin America; Middle East & Africa – Algeria, Egypt, Israel, Kuwait, Nigeria, Saudi Arabia, South Africa, Turkey, United Arab Emirates, & Rest of MEA
    Competitive Landscape Thermo Fisher Scientific Inc, Cell Applications Inc, Axol Biosciences Ltd, Cytori Therapeutics Inc, STEMCELL Technologies, Cyagen Biosciences, Celprogen Inc, BrainStorm Cell Limited, Stemedica Cell Technologies Inc, Merck KGaA (MilliporeSigma), PromoCell GmbH
    Customization Scope Customization for segments, region/country-level will be provided. Moreover, additional customization can be done based on the requirements.
    Purchase Options We have three licenses to opt for: Single User License, Multi-User License (Up to 5 Users), Corporate Use License (Unlimited User and Printable PDF)

    Frequently Asked Questions (FAQ)

    What is the size of the mesenchymal stem cells market in 2023?

    The mesenchymal stem cells market size is USD 3 billion in 2023.

    What is the projected CAGR at which the mesenchymal stem cells market is expected to grow at?

    The mesenchymal stem cells market is expected to grow at a CAGR of 12.6% (2024-2033).

    List the segments encompassed in this report on the mesenchymal stem cells market?

    Market.US has segmented the mesenchymal stem cells market by geographic (North America, Europe, APAC, South America, and Middle East and Africa). By Workflow the market has been segmented into Cell Sourcing & Isolation, Culture & Cryopreservation, Differentiation, Characterization. By Source of Isolation the market has been segmented into Bone Marrow, Cord Blood, Peripheral Blood, Fallopian Tube, Fetal Liver, Lung, Adipose Tissue. By Indication the market has been segmented into Bone and Cartilage repair, Cardiovascular Diseases, Inflammatory And Immunological Diseases, Liver Diseases, Cancer, Others. By Application the market has been segmented into Disease Modeling, Drug Development & Discovery, Stem Cell Banking, Tissue Engineering, Toxicology Studies, Others.

    List the key industry players of the mesenchymal stem cells market?

    Thermo Fisher Scientific Inc, Cell Applications Inc, Axol Biosciences Ltd, Cytori Therapeutics Inc, STEMCELL Technologies, Cyagen Biosciences, Celprogen Inc, BrainStorm Cell Limited, Stemedica Cell Technologies Inc, Merck KGaA (MilliporeSigma), PromoCell GmbH, and other key players.

    Which region is more appealing for vendors employed in the mesenchymal stem cells market?

    North America is expected to account for the highest revenue share of 36.2% and boasting an impressive market value of USD 3.2 billion. Therefore, the mesenchymal stem cells industry in North America is expected to garner significant business opportunities over the forecast period.

    Name the key areas of business for mesenchymal stem cells?

    The US, Canada, India, China, UK, Japan, & Germany are key areas of operation for the mesenchymal stem cells Market.

    Which segment accounts for the greatest market share in the mesenchymal stem cells industry?

    With respect to the mesenchymal stem cells industry, vendors can expect to leverage greater prospective business opportunities through the pharmaceutical segment, as this area of interest accounts for the largest market share.

    Mesenchymal Stem Cells Market
    Mesenchymal Stem Cells Market
    Published date: Nov 2023
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    • Thermo Fisher Scientific Company Profile
    • Cell Applications Inc
    • Axol Biosciences Ltd
    • Cytori Therapeutics Inc
    • STEMCELL Technologies
    • Cyagen Biosciences
    • Celprogen Inc
    • BrainStorm Cell Limited
    • Stemedica Cell Technologies Inc
    • Merck KGaA (MilliporeSigma)
    • PromoCell GmbH
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